X2, artificial can have its moments, they do work. But as far as effectiveness vs. the real deal go with live bait every single time. I carry artificial with me at all times. I only pull it out if the bite is really hot and the fish aren't fussy or if I happen to run out or run low of live ones. That said doing a combo can be very effective as well. Start by putting on artificial maggots to load up your spoon or jig and then tip with a couple live ones. You can conserve live bait this way and you get double the attraction benefits with a very durable offering you don't have to re-bait a ton all the time. Again if the bite is hot and you have fish underneath you, you need to get up and down like you are saving lives so artificial is great in that situation too, as they can't pick them off the hook as easily and you can get back down there quickly to yard another one up. Good luck!
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