Thanks to all the responses so far.
I realize that most shoot this with cup and core - I don't want to hunt with these and will go leadless.
Going to order a box of each of the 250 and 300 and work up load for each using the published Barnes data at the minimum charge as a starting point and then titrate up if appropriate.
250
N120 Min=50gr
IMR4227 Min=43gr
300
N120 Min=44gr
IMR4227 Min=38.5gr
Will see what I get off the Garmin and Shotmarker.
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