I'm willing to poke the bear,,,,,, a 243 is the best,,,, with a well placed shot and a quality bullet, it will kill anything everywhere,,,,,lol ok for real now, it upsets me to think you are planning on one gun only but if that was so then I would choose the 06,, but,,,,, if you eventually plan on another one then go for a 25-06 or the 7mm08 and then your second could be 300 win mag,,,, the 30-06 would be an overlap of them both
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