I used to run all my traditional BP cartridge rifles like the 40/65,45/70, and 45/110 at BP velocities and never had an issue with recoil, or killing power .
I never tried to kill stuff over 200 yards with them however .
Cat
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Anytime I figure I've got this long range thing figured out, I just strap into the sling and irons and remind myself that I don't! 
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