Spinning rods are meant to be eyes down always. It drives me insane every time I see someone fishing with a spinning rod upside down and reeling backwards
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Rods are set up for the reel style but it is the eyes that are different and this is because the line comes off a spinning reel in big loops so it starts with bigger eyes
I don’t know if there is any difference blank wise or if you gain any benefit to eyes up or down when fighting a fish. I have reached the extent of my knowledge on this so hopefully someone smarter comes along to help.