used it for years, sometimes i still do. they can put some good holes in coyotes if you hit them wrong or the bullet can just disappear.
the only reason i switched is because i don't care about hides and i built a 220 ai swift. in this case i would prefer my 22-250 to my 223
a flatter shot can help a lot if the coyote comes in fast and you don't have time to range. so you might prefer the 22-250 but ammo will cost more
i'm sure ~90% of rifles that come in 223 also come in 22-250
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