You are right, speed affects trajectory. Ballistic coefficient greatly affects downrange speed. To compare you would need to compare similar shaped bullets. The best I found on the Federal premium site was a 100 gr. Nosler Ballistic Tip to a 130 gr. Sierra Boat Tail. The lighter, faster 25-06 round was 2.3" flatter at 500 yards. I do believe though that the Nosler is a slightly more efficient bullet.
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