I've never done it, and I don't know if I would do it personally, but really, when it comes down to it, it depends on how confident I would be on the shot, given distance and position of the animal (and how "relaxed" it appears).
If it's on high alert, for example, then no...
I'm looking for that window like in the picture below. Not always easy to judge. Buf if you get it right, it is devastating. Look at all of those blood vessels etc.
