All .204 R. factory barrels are 1:12 twist as far as I know, most if not all will stabilize up to 39 grain bullets about half will do 40 grainers.
Slow twists are for lighter bullets ,generally speaking, faster for heavier.
Berger made (makes) a 55 grain .20 cal. that requires a 1:9 twist.
There is an abundance of info online comparing .204 Ruger /.223 Rem. performance/ballistics
Considering the ammo situation as of late, if you're not reloading, that would be a major influence on deciding calibres / cartridges. IMHO
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