Prdtgttr makes a number of good points. I shoot 55 grain Nosler ballistic tips in my 26" heavy barrel 22.250. There are only two shots to take, one with the coyote directly facing you, hit em squarely in the chest, Rare is the time you will find an exit hole, so max fur value. Second is exactly broadside, hit em in the widest part of the body, half way up. The area behind the shoulder is too small, and you might clip a front leg. Have a hard look at the first one you skin, without its' clothes on. The target is the size of a tennis ball, the rest is fur. I sight in 1/4" high at 100 yards, allowing dead on aim out to about 250 yards, this way I don't ruin hides on close, easy shots due to a high hit, ie. the backbone. I too am passionate about this, and have been at it for a good long time. Hope this helps, and good luck.

Regards,

Critter